Showing posts with label alcohol. Show all posts
Showing posts with label alcohol. Show all posts

11 Nov 2011

Women suffer quicker brain damage from alcohol abuse

Women alcoholics suffer damage to the part of their brain that controls moods, impulses and sleep three times faster than their male counterparts, a Swedish study showed Wednesday.
Women suffer a 50-percent reduction in the so-called serotonin function in their brain after four years of excessive drinking, while men show the same amount of damage after 12 years of alcohol abuse, according to the study by researchers at Gothenburg University.
"The impairment is progressing much faster in women," explained Kristina Berglund, who conducted the study with colleagues from the university's Department of Psychology, as well as two researchers at the faculty of Health Sciences, known as the Sahlgrenska Academy.
Serotonin is a brain neurotransmitter that is, among other things, critical to the development and treatment of depression and chronic anxiety.
It also regulates impulse control and our ability to fall asleep and stay awake.
The researchers studied several brain functions of 42 people -- a third of them women -- who admitted to alcohol dependency, along with 28 control subjects.
"We saw that the alcohol dependent individuals had significantly lower serotonin functions," Berglund told AFP.
The women tested said they on average had been drinking the equivalent of about 12 bottles of wine a week for four years, while the men had been drinking the same amount, but for 12 years.
However, "we could see the damage to the serotonin function was equal between men and women," Berglund said.
The results, which are scheduled to be published in the journal of Alcoholism: Clinical and Experimental Research in January, had come as a partial surprise to the researchers, she said.
"We were not surprised to find that the serotonin function was impaired in the alcohol-dependent individuals, but we were surprised to see that women were so much more vulnerable, even in the brain," she said.
Ulf Berggren, one of the Sahlgrenska Academy contributors to the study, meanwhile stressed that while the timing was different, men ultimately suffered the same degree of harm to their serotonin function as women.
The study authors acknowledged more research was needed, especially since they had used such a small number of test subjects.
Berglund also said that while the researchers had connected significant serotonin function harm to alcohol abuse, they still needed to look at the psychological impact of the damage.
"We know this function is significantly impaired, but what does this mean? What are the consequences? That's a question that needs answering," she said.
(via AFP)
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26 Oct 2011

Strawberries protect stomach from alcohol

In an experiment on rats, European researchers have proved that eating strawberries reduces the harm that alcohol can cause to the stomach mucous membrane. Published in the open access journal Plos One, the study may contribute to improving the treatment of stomach ulcers.
A team of Italian, Serbian and Spanish researchers has confirmed the protecting effect that strawberries have in a mammal stomach that has been damaged by alcohol. Scientists gave ethanol (ethyl alcohol) to laboratory rats and, according to the study published in the journal Plos One, have thus proved that the stomach mucous membrane of those that had previously eaten strawberry extract suffered less damage.
Sara Tulipani, researcher at the University of Barcelona (UB) and co-author of the study explains that “the positive effects of strawberries are not only linked to their antioxidant capacity and high content of phenolic compounds (anthocyans) but also to the fact that they activate the antioxidant defences and enzymes of the body.”
The conclusions of the study state that a diet rich in strawberries can have a beneficial effect when it comes to preventing gastric illnesses that are related to the generation of free radicals or other reactive oxygen species. This fruit could slow down the formation of stomach ulcers in humans.
Gastritis or inflammation of the stomach mucous membrane is related to alcohol consumption but can also be caused by viral infections or by nonsteroidal anti-inflammatory medication (such as aspirin) or medication used to treat against the Helicobacter pylori bacteria.
Maurizio Battino, coordinator of the research group at the Marche Polytechnic University (UNIVPM, Italy) suggests that “in these cases, the consumption of strawberries during or after pathology could lessen stomach mucous membrane damage.”
The team found less ulcerations in the stomachs of those rats which had eaten strawberry extract (40 milligrams/day per kilo of weight) for 10 days before being given alcohol.
Battino emphasises that “this study was not conceived as a way of mitigating the effects of getting drunk but rather as a way of discovering molecules in the stomach membrane that protect against the damaging effects of differing agents.”
Treatments for ulcers and other gastric pathologies are currently in need of new protective medicines with antioxidant properties. The compounds found within strawberries could be the answer.
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